Table 2.
Changes of Dopaminergic Markers in Peripheral Blood Lymphocytes in Parkinson's Disease. The Table Summarizes the Methodology Applied and the Findings Obtained. DA=Dopamine, DAT=Dopamine Transporter
| Authors | Methodology | Findings |
|---|---|---|
| Le Fur et al. [74] | Receptor binding assay | Decreased D2-like receptor |
| Nagai et al. [78] | RT-PCR and Receptor binding assay | Decreased D3 receptor |
| Barbanti et al. [79] | Receptor binding assay | Increased D3 and D5 receptors |
| Caronti et al. [80] | Immunochemistry, HPLC with electrochemical detection | Decreased TH immunoreativity, Decreased intracellular DA concentration |
| Caronti et al. [81] | Immunochemistry | Decreased DAT immunoreactivity |
| Pellicano et al. [82] | Immunochemistry | Decreased DAT immunoreactivity |
| Buttarelli et al. [84] | Immunochemistry | Decreased DAT immunoreactivity |
| Pontieri and Colosimo [85] | Immunochemistry | Decreased DAT immunoreactivity |