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Hematoxylin and eosin staining of liver tissue from hamsters fed with hyperlipidemic diets. Magnification 400×. A) Normal diet, B) diet adequate in methionine and choline (5A4C), C) diet deficient in methionine and choline (5D4F), and D) diet adequate in methionine and deficient in choline (5D4E). Hepatocytes are filled with microvascular and macrovesicular fat deposits, leaving the nuclei in a central position, and the hepatocytes have assumed a very foamy appearance.
