Table 1.
Profile of the normal and hypercholesterolemic test diets
| LabDiet® reference rodent laboratory chow | Modified LabDiet laboratory rodent test diet | |||
|---|---|---|---|---|
| Nutritional profile | 5001 | 5A4C | 5D4F | 5D4E |
| Protein, % | 23.9 | 25 | 15.1 | 22.5 |
| Fat (ether extract), % | 5 | 10.3 | 10 | 10.2 |
| Total saturated fatty acids, % | 1.56 | 6 | 6 | 5.89 |
| Total monounsaturated fatty acids, % | 1.6 | 2.10 | 1.24 | 2.10 |
| Polyunsaturated fatty acids, % | 1.42 | 1.15 | 2.19 | 0.87 |
| Cholesterol, ppm | 200 | 500 | 500 | 500 |
| Linoleic acid, % | 1.22 | 1.57 | 2.16 | 1.60 |
| Omega-3 fatty acid, % | 0.19 | 0.19 | 0.03 | 0.14 |
| Choline chloride, ppm | 2250 | 2299 | 0.00 | 1200 |
| Methionine, % | 0.67 | 0.43 | 0.13 | 0.4 |
| Fiber, % | 5.1 | 5.1 | 0.0 | 4.6 |
| Nitrogen-free extract, % | 48.7 | 42.5 | – | 46.4 |
| Starch, % | 31.9 | 28.37 | – | 36.89 |
| Sucrose, % | 3.70 | 2.21 | – | 1.34 |
| Total digestible nutrients, % | 76 | 81 | – | 80.9 |
| Calories provided by: | ||||
| Protein, % | 28.5 | 27.5 | 14.4 | 24.5 |
| Fat, % | 13.5 | 25.6 | 21.3 | 25 |
| Carbohydrates, % | 57.9 | 46.9 | 64.3 | 50.6 |
Abbreviations: 5A4C, diet adequate in methionine and choline levels; 5D4F, diet deficient in methionine and devoid of choline; 5D4E, diet deficient in choline but with adequate levels of methionine.