Table 3.
Independent effect of intron 2 SNPs in the carriers of the 3' UTR risk genotypesa
| Risk genotype | Study group, n (%) | ||||||
|---|---|---|---|---|---|---|---|
| rs3853839 | rs179019 | rs179010 | SLE (N = 322) | Controls (N = 243) | P | OR | 95% CI |
| G/G or G/C | A/A | T/T | 42 (13.0) | 14 (5.8) | |||
| + | + | + | 280 (87.0) | 229 (94.2) | 0.0043 | 2.45 | 1.31 to 4.60 |
| + | Others | Reference | |||||
aSNP, single-nucleotide polymorphism; 3' UTR, 3' untranslated region; OR, odds ratio; 95% CI, 95% confidence interval. Genotype frequencies are shown in parentheses (%). P value was calculated using Fisher's exact test.