Table 1.
Gender (M:F) | 110:113 |
Age at diagnosis (years, mean ± SD) | 43.1 ± 10.0 |
Disease duration (years, mean ± SD) | 12.8 ± 9.2 |
Clinical manifestations | n (%) |
Oral ulcer | 223 (100) |
Genital ulcer | 159 (71.3) |
Skin lesions | 180 (80.7) |
Positive pathergy test | 94/182 (51.6) |
Uveitis | 85 (38.1) |
Retinal vasculitis | 10 (4.5) |
Joint involvement | 125 (56.1) |
Vascular involvement | 33 (14.8) |
Central nervous system involvement | 10 (4.5) |
HLA-B*51† | 81 (36.3) |
†HLA-B*51 in controls = 282/1,398 (20.2%); P < 0.0000001; SD, standard deviation.