Table 4.

Changes in neuromediators and their receptors

	rhOP-1 vs Cntr	OP-1AS vs Cntr
	fold change	fold change	Accession no.
Bradykinin Rβ1	1.85↓	1.59↑	[GenBank:NM_000710]
Bradykinin Rβ2	1.68↓		[GenBank:NM_000623]
Tachykinin R1	1.64↓		[GenBank:NM_001058]
Nerve growth factor-β	1.93↓		[GenBank:NM_002506]
Tachykinin1 precursor (Substance K, Substance P)	2.26↓