Table 3.
GO category | GO ontology | GO term | LS permutation P-value |
---|---|---|---|
GO:0002820 | BP | Negative regulation of adaptive immune response | 0.00001 |
GO:0033077 | BP | T cell differentiation in the thymus | 0.00001 |
GO:0043383 | BP | Negative T cell selection | 0.00001 |
GO:0045061 | BP | Thymic T cell selection | 0.00001 |
The dataset showed two key immune-associated pathways to be altered, "negative regulation of adaptive immune response" and several ontologies affecting "thymic T cell selection" both with P-values <0.005.