Table 2.
Deviated GO Biological Process gene categories of downregulated genes in peripheral blood of SLE patients
| Gene category | List hits (n = 1,429) | Population hits (n = 13,802) | EASE score (<0.01) |
|---|---|---|---|
| Sensory perception | 56 | 383 | 7.49 × 10-3 |
| Perception of sound | 21 | 82 | 2.00 × 10-4 |
| Hearing | 20 | 81 | 4.86 × 10-4 |
| Response to radiation | 36 | 222 | 7.48 × 10-3 |
| Response to light | 35 | 207 | 4.39 × 10-3 |
| Calcium ion transport | 16 | 66 | 2.57 × 10-3 |
| Macromolecule biosynthesis | 131 | 1,002 | 3.38 × 10-3 |
| Protein biosynthesis | 90 | 650 | 3.38 × 10-3 |
Deviated Gene Ontology database (GO) Biological Process gene categories of downregulated genes in peripheral blood of systemic lupus erythematosus (SLE) patients compared with healthy individuals. EASE, Expression Analysis Systematic Explorer software, version 2.0.