Table 1.
Characteristics of study population by gender and serum uric acid quartile
| Women (n = 1,287) | Men (n = 1,211) | |||||||
|---|---|---|---|---|---|---|---|---|
| Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |
| sUA range, μmol/L [mg/dL] | 77-196 [1.3-3.3] | 196-226 [3.3-3.8] | 232-274 [3.9-4.6] | 280-636 [4.7-10.7] | 155-291 [2.6-4.9] | 297-333 [5.0-5.6] | 339-393 [5.7-6.6] | 399-690 [6.7-11.6] |
| Age, years | 40.1 (3.8) | 40.1 (3.6) | 40.3 (3.6) | 40.5 (3.8) | 40.1 (3.6) | 39.8 (3.5) | 40.4 (3.5) | 40.4 (3.6) |
| African-American | 43.5% | 42.6% | 46.5% | 57.5% | 42.7% | 37.4% | 42.5% | 43.2% |
| Body mass index, kg/m2 | 24.8 (4.7) | 27.2 (6.2) | 29.6 (6.8) | 33.1 (7.2) | 26.1 (3.8) | 27.4 (4) | 28.1 (4.5) | 30.1 (4.6) |
| Alcohol, mL/day | 6.2 (10) | 5.7 (11.8) | 9 (32.7) | 9.1 (22) | 13.3 (35.4) | 14.2 (25.1) | 16.2 (24.4) | 20.3 (35.1) |
| Smokers | 36.6% | 39.7% | 38% | 46.2% | 35.3% | 39.4% | 39.3% | 40.2% |
| Systolic BP, mm Hg | 107 (12.5) | 109.3 (14) | 112.4 (15.3) | 115.5 (16.3) | 111.7 (11.2) | 114.8 (13.5) | 115.4 (12.9) | 118.3 (14.7) |
| Diastolic BP, mm Hg | 69.6 (10.1) | 71.5 (10.2) | 73.3 (10.9) | 75.9 (12.6) | 73.3 (9.2) | 76.3 (11) | 76.8 (10.2) | 79.2 (12.1) |
| Serum fasting glucose, mmol/L [mg/dL] | 4.45 (0.40) [80.2 (7.2)] | 4.48 (0.43) [80.7 (7.7)] | 4.5 (0.45) [81.1 (8.1)] | 4.7 (0.53) [84.3 (9.5)] | 4.7 (0.46) [84 (8.3)] | 4.8 (0.53) [85.7 (9.6)] | 4.8 (0.52) [86.4 (9.4)] | 4.9 (0.54) [88.8 (9.7)] |
| Serum HDL-C, mmol/L [mg/dL] | 1.54 (0.33) [59.7 (12.8)] | 1.44 (0.35) [55.5 (13.5)] | 1.45 (0.36) [56 (14.1)] | 1.32 (0.37) [51 (14.4)] | 1.24 (0.33) [48 (12.9)] | 1.19 (0.32) [45.9 (12.4)] | 1.14 (0.31) [43.9 (11.8)] | 1.10 (0.33) [42.4 (12.6)] |
| Serum LDL-C, mmol/L [mg/dL] | 2.72 (0.73) [105.1 (28.2)] | 2.74 (0.74) [105.9 (28.7)] | 2.80 (7.7) [108.4 (29.8)] | 3.01 (0.79) [116.3 (30.6)] | 2.87 (0.74) [110.9 (28.5)] | 3.12 (0.81) [120.5 (31.5)] | 3.19 (0.95) [123.5 (36.6)] | 3.23 (0.92) [125 (35.7)] |
| Serum triglycerides, mmol/L [mg/dL] | 0.78 (0.38) [68.8 (33.8)] | 0.89 (0.44) [78.7 (39.1)] | 0.95 (0.52) [84.5 (45.8)] | 1.27 (0.80) [112.6 (70.7)] | 1.01 (0.67) [89.8 (59.7)] | 1.26 (0.76) [111.5 (67.4)] | 1.52 (1.87) [135 (165.7)] | 1.86 (1.76) [164.8 (156.1)] |
| Serum creatinine, μmol/L [mg/dL] | 79.6 (8.8) [0.9 (0.1)] | 79.6 (8.8) [0.9 (0.1)] | 79.6 (8.8) [0.9 (0.1)] | 79.6 (8.8) [0.9 (0.1)] | 97.2 (8.8) [1.1 (0.1)] | 97.2 (8.8) [1.1 (0.1)] | 97.2 (17.7) [1.1 (0.2)] | 97.2 (17.7) [1.1 (0.2)] |
| Waist circumference, cm | 76.6 (10.1) | 81.6 (12.1) | 86.3 (13.1) | 94 (14.1) | 87.8 (9.5) | 91.8 (9.6) | 93.5 (11) | 98.4 (10.9) |
| eGFR, abbreviated MDRD | 87.2 (15.1) | 85.6 (15.5) | 83.9 (14.2) | 82.7 (15.2) | 89.9 (13.6) | 88.3 (14.1) | 87.1 (19.3) | 85.6 (16.1) |
| Framingham risk score | -4.8 (4.1) | -3.7 (4.3) | -3.3 (4.4) | -1.4 (4.3) | 1.1 (2.2) | 1.8 (2.4) | 2.3 (2.3) | 2.7 (2.4) |
| C-reactive protein, mg/dL | 1.5 (2.9) | 1.5 (1.7) | 1.6 (2.9) | 1.8 (1.7) | 1.7 (2.9) | 1.8 (2.0) | 2.0 (2.5) | 2.1 (2.5) |
Data are presented as range, mean (standard deviation), or percentage. BP, blood pressure; eGFR, estimated glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; MDRD, modification of diet in renal disease; sUA, serum uric acid.