Table 3.
Comparison of differential gene expression values determined by relative quantitative-polymerase chain reaction and microarray analyses
| Gene | RQ-PCRa | Microarraya | ||
|---|---|---|---|---|
| Affected | Unaffected | Affected | Unaffected | |
| TNFAIP6 | 3.04 | 2.17 | 2.24 | 2.15 |
| TNFSF10 | 1.50 | 1.37 | 1.58 | 1.33 |
| MAP2K6 | 1.20 | 1.20 | 1.38 | 1.21 |
| IL1RN | 1.37 | 1.21 | 1.67 | 1.17 |
| IFI27 | 1.20 | 2.01 | 7.24 | 6.21 |
| ANXA3 | 3.18 | 1.82 | 2.79 | 2.43 |
| CEACAM6 | 5.70 | 1.15 | 4.70 | 1.10 |
| DEFA4 | 7.01 | 1.47 | 2.32 | 1.18 |
| EIF2AK2 | 2.20 | 1.12 | 2.36 | 1.70 |
| FCERA1 | -1.82 | -1.48 | -1.76 | -1.22 |
| SYTL2 | -1.93 | -1.61 | -1.49 | -1.10 |
| LGR6 | -1.25 | -1.13 | -1.64 | -1.11 |
| KRTCAP2 | -1.20 | -1.20 | -1.16 | -1.07 |
| LTK | 1.02 | 1.21 | 2.32 | 1.06 |
| FYN | 1.23 | 1.19 | -1.26 | -1.01 |
aFold change values indicating increased (positive value) or decreased (negative value) levels of gene expression in systemic autoimmune disease-affected or -unaffected twins compared with unrelated, matched controls. RQ-PCR, relative quantitative-polymerase chain reaction.