Table 3.

Salmonella Typhimurium Genes Involved in Biofilm Formation That Are Regulated by luxS/Autoinducer-2 at Mid-Log Phase in the Absence of Glucose

Genes	Putative identification of JCVI database	Fold change (W/M)	Fold change (wCFS/mCFS)
csgA	Curlin major subunit, coiled surface structures cryptic	1.1	−1.1
csgC	Putative curli production protein	1.2	1.0
bcsA	Glycosyltransferase, probably involved in cell wall biogenesis	−1.8	1.0
bcsC	Endo-1,4-D-glucanase	−1.8	−1.0
yhjN	Putative cellulose synthase	−1.6	−1.0
fimA	Major type 1 subunit fimbrin (pilin)	2.0	−1.0
fimD	Outer membrane usher protein	−1.3	1.1
fimZ	Fimbrial protein Z, putative transcriptional regulator (LuxR/UhpA)	1.5	−1.1
fimW	Putative fimbrial protein	1.4	1.0
fimY	Putative regulatory protein	1.3	1.1
lpfA	Long polar fimbria	1.4	−1.1
lpfE	Long polar fimbrial minor protein	1.2	−2.2
yojN	Putative sensor/kinase in regulatory system	1.6	1.1

Differentially regulated genes between wild type (W) and ΔluxS mutant (M) and between wild-type cell-free supernatants and ΔluxS mutant cell-free supernatants are listed. Genes that have the same direction of regulation in both W/M and wCFS/mCFS are regulated by AI-2 and are shown in bold.