Table 2.
Marker | Disease-associated allele | Allele frequency | No. of case-pseudocontrol sets | Pa | OR (95% CI) |
El-Rugan village, Sudan | |||||
PHF10/rs4073926 | T | 0.44 | 37 | .010b | 2.45 (1.24–4.86) |
PHF10/rs9371126 | T | 0.75 | 43 | .809 | 1.14 (0.39–3.37) |
C6orf70/rs4145078 | G | 0.3 | 54 | .154 | 1.67 (0.83–3.36) |
C6orf70/rs4716396 | C | 0.37 | 58 | .043b | 2.07 (1.02–4.21) |
DLL1/rs1028488 | G | 0.51 | 48 | .355 | 1.21 (0.81–1.80) |
DLL1/rs1884190 | T | 0.56 | 22 | .085 | 1.5 (0.95–2.38) |
DLL1/rs2738822 | T | 0.39 | 35 | .021b | 1.75 (1.09–2.82) |
DLL1/rs2738820 | A | 0.32 | 46 | .019b | 1.69 (1.09–2.62) |
DLL1/rs9459988 | T | 0.52 | 49 | .004b | 2.20 (1.29–3.76) |
DLL1/rs17860704 | C | 0.81 | 31 | .001b | 3.25 (1.61–6.57) |
FAM120B/rs9366198 | C | 0.55 | 65 | .203 | 1.39 (0.84–2.31) |
FAM120B/rs9460106 | C | 0.48 | 46 | >.999 | 1 (0.53–1.90) |
FAM120B/2103816 | A | 0.43 | 53 | .192 | 1.38 (0.85–2.22) |
FAM120B/rs9295407 | A | 0.91 | 39 | .071 | 3.5 (0.9–13.6) |
PSMB1/rs6914744 | C | 0.29 | 56 | .008b | 2.40 (1.25–4.60) |
PSMB1/rs12717 | C | 0.26 | 58 | .254 | 1.57 (0.72–3.42) |
TBP/rs13207114 | G | 0.4 | 51 | .026b | 1.79 (1.07–2.99) |
TBP/rs6937840 | G | 0.21 | 67 | .91 | 1.05 (0.47–2.32) |
Brazil | |||||
PHF10/rs4073926 | C | 0.49 | 59 | .903 | 1.04 (0.55–1.95) |
C6orf70/rs4145078 | A | 0.68 | 39 | .804 | 1.07 (0.62–1.85) |
DLL1/rs2738822 | T | 0.46 | 79 | .383 | 1.24 (0.77–1.98) |
DLL1/rs2738820 | A | 0.46 | 94 | .56 | 1.14 (0.73–1.79) |
DLL1/rs9459988 | G | 0.13 | 76 | .402 | 1.56 (0.55–4.38) |
DLL1/rs17860704 | C | 0.91 | 80 | .047b | 3 (1.01–8.86) |
PSMB1/rs6914744 | A | 0.62 | 45 | .131 | 1.53 (0.88–2.65) |
TBP/rs13207114 | A | 0.67 | 56 | .428 | 1.27 (0.7–2.31) |
NOTE. Robust CLOGIT odds ratios (ORs) and 95% confidence intervals (CIs) for allele-wise associations are shown. Single-nucleotide polymorphisms genotyped in the Brazilian sample were those with evidence for positive associations in El-Rugab village in Sudan.
One degree of freedom.
Positive associations at nominal P < .05.