Table 3.
Known Single-nucleotide Polymorphisms (SNPs) Within Conserved Noncoding Sequence (CNS) Peaks in the Region Spanning From the 5′ Untranslated Region to 8.8 kb Upstream of DLL1
| SNP | Physical position, bp | Position between markers, bp | CNS peaka | Alleles | MAFb |
| rs2738820c | 170601259 | 0 | 3 | C/A | CEU, 0.37; YRI, 0.32; DIL, 0.45; El-Rugab, 0.36 |
| rs17860704c | 170602429 | 1170 | 5 | T/C | YRI, 0.1; DIL, 0.01; El-Rugab, 0.19 |
| rs17860703 | 170602438 | 9 | 5 | G/A | DIL, 0.01; El-Rugab, 0 |
| rs57618361 | 170602477 | 39 | 5 | A/G | El-Rugab, 0 |
| rs34733288 | 170602979 | 502 | 6 | C/A | El-Rugab, 0 |
| rs73790663 | 170603272 | 293 | 6 | G/A | El-Rugab, 0 |
| rs9348307 | 170603985 | 713 | 7 | G/C | CEU, 0.2; YRI, 0; DIL, 0.16 |
| rs12200136 | 170605058 | 1073 | 8 | G/A | |
| rs77087564 | 170605086 | 28 | 8 | G/A | CEU, 0.17 |
| rs79819098 | 170606572 | 1486 | 10 | G/T | |
| rs35020594 | 170606633 | 61 | 10 | C/A | |
| rs76301666 | 170606709 | 76 | 11 | G/T | CEU, 0.14 |
| rs78981869 | 170607126 | 417 | 12 | G/T | YRI, 0.02 |
| rs76345779 | 170607215 | 89 | 12 | T/G | |
| rs77088136 | 170607218 | 3 | 12 | A/T | |
| rs34203352 | 170607258 | 40 | 12 | −/A | |
| rs79394597 | 170608750 | 1492 | 13 | G/A | YRI, 0.04 |
| rs60935272 | 170608860 | 110 | 13 | G/A |
NOTE. Physical positions are given for build 37.1 of the human genome. MAF, minor allele frequency.
a
Peaks are numbered in Figure 4.
b
Includes data from HapMap Utah residents with ancestry from northern and western Europe (CEU) and Yoruba individuals in Ibadan, Nigeria (YRI) [12], and data from 96 Caucasian European control individuals (DIL) [41].
c
SNPs genotyped in this study.