Table 1.

Criteria for adherence to guidelines

	ACMG 2001	CAP 2002	GHC 2002
First episode of VTE	Age younger than 50 yr	Age younger than 50 yr	Age younger than 50 yr and idiopathic
	Any age if family history of VTE	Any age, unprovoked	Age younger than 50 yr and strong family history of DVT
	If pregnant or taking o.c.	Any age, if family history of VTE at age younger than 50 yr	If pregnant
	Age older than 50 yr if no malignancy	If pregnant, postpartum, taking o.c. or HRT
Recurrent VTE	Yes	Yes	Same criteria as first episode of VTE
VTE at unusual site	Yes	Yes	Same criteria as first episode of VTE
Pregnancy outcome (other than fetal loss)	Unexplained severe pre-eclampsia, IUGR, or placental abruption	No	NA
Fetal loss	If recurrent or stillbirth	If unexplained and in second or third trimester	NA
Arterial thrombosis (including stroke)	No (except if age younger than 50 yr and no other risk factors)	No (except if unexplained and no risk factors or in young smokers)	NA
Myocardial infarction	Females if age younger than 50 yr	No	NA
Family history of FVL	Yes	Yes	Only if first-degree relatives
Family history of VTE	If VTE at age younger than 50 yr	No	No

o.c., oral contraceptives; HRT, hormone replacement therapy; IUGR, intrauterine growth retardation; NA, indicates that this testing indication was not covered in the text of the guidelines; No, indicates that the guidelines do not recommend testing for this indication.