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Schematic representation of members of the RecQ DNA helicase family. The proteins shown are E.coli RecQ, S.cerevisiae Sgs1p, S.pombe Rqh1 and human BLM, WRN and RecQL. The size of each protein is shown on the right. The conserved central helicase domain is shown as a black box; clusters of acidic residues are indicated by hatched boxes; and the exonuclease domain in WRN is indicated by a gray box.
