Skip to main content
. 2001 Apr 15;29(8):1765–1771. doi: 10.1093/nar/29.8.1765

Figure 4.

Figure 4

Porphyrins are potent inhibitors of E.coli RecQ helicase activity. (A) Schematic representation of the molecular structures of a G-quartet and porphyrin analogs T4 and NMM. (B) Inhibition of RecQ helicase activity by T4. Unwinding by RecQ (10 nm) was assayed on 32P-labeled G4 DNA or duplex DNA substrates in the presence of the indicated amounts of T4. (C) Inhibition of RecQ helicase activity by NMM. Unwinding by RecQ (10 nm) was assayed on 32P-labeled G4 DNA or duplex DNA substrates in the presence of the indicated amounts of NMM.