Table 1. Substrate-specificity of RecQ helicase inhibitors.

Inhibitor	G4 DNA unwinding inhibition constant (µM)	Duplex DNA unwinding inhibtion constant (µM)
T4	4.6	21.8
NMM	1.7	>100

Inhibition constants shown were determined as the concentration at which unwinding activity was inhibited by 50%. Values are means of two or more experiments.