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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Pediatr Res. 2010 Dec;68(6):519–525. doi: 10.1203/PDR.0b013e3181f90278

Figure 4. L-Citrulline improves lung angiogenesis in O2-induced BPD in newborn rats.

Figure 4

Capillary density, as quantified by the number of barium-filled pulmonary arteries counted per high-power field, was significantly decreased in hyperoxia-exposed lungs compared with room air controls. Treatment with L-citrulline preserved lung capillary density in experimental BPD. N=5/group, §P<0.0001 hyperoxia vs normoxia and normoxia+L-Citrulline, **P<0.001 hyperoxia vs hyperoxia+L-Citrulline, *P<0.02 normoxia+L-Citrulline vs hyperoxia+L-Citrulline.