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The resistant factors and reversal index of K562 and KA cells to Fe3O4 nanoparticles
| IC50 mol/L |
Resistant factors | Reversal Index | ||
|---|---|---|---|---|
| K562 | KA | |||
| DNR | 7.94±0.76×10−6 | 39.72±2.95×10\−6 | 5.00 | |
| Fe3O4+DNR | 3.95×10−6 | 3.18×10−6 | 0.80 | 6.25 |
Resistant factor (Rf) = [IC50] KA/[IC50] K562; Reversal index (Ri) = [Rf]/[Rf′], where Rf and Rf′ stand for the resistant factor of KA with DNR alone and Fe3O4 nanoparticle with DNR, respectively.
