. Author manuscript; available in PMC: 2012 Jul 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Apr 28;20(7):1303–1314. doi: 10.1158/1055-9965.EPI-11-0037

Table 2.

Odds Ratios (OR) and 95% confidence intervals (CI) for increased cytokine concentrations in NHL cases

	>3 years prior			1–3 years prior			0–1 year prior
	N, sets^a	OR^b	95% CI	N, sets^a	OR^b	95% CI	N, sets^a	OR^b	95% CI

	all NHL cases vs. HIV+ controls^c

IL6	132	2.37	1.51 – 3.72	129	4.14	1.81 – 9.49	88	6.01	2.07 – 17.45
CRP	141	1.65	1.25 – 2.18	139	1.55	1.08 – 2.22	100	1.31	0.84 – 2.07
sCD27	141	3.72	1.68 – 8.25	139	6.98	2.23 – 21.83	100	3.81	1.21 – 11.96
sCD30	141	3.22	1.75 – 5.91	139	8.64	3.09 – 24.14	101	4.77	1.63 – 13.90
sCD23	136	2.02	1.17 – 3.47	136	1.74	0.93 – 3.26	99	1.37	0.78 – 2.42
IgE	141	1.08	0.88 – 1.31	139	0.99	0.78 – 1.25	100	0.98	0.76 – 1.27
IL10	141	0.78	0.17 – 3.64	139	1.26	0.28 – 5.57	100	7.74	1.06 – 56.59

	NHL after other AIDS diagnosis vs. AIDS controls^d

IL6	79	1.00	0.60 – 1.69	81	2.08	1.13 – 3.86	49	1.47	0.90 – 2.40
CRP	82	1.34	0.94 – 1.92	86	1.34	0.98 – 1.85	54	1.03	0.77 – 1.38
sCD27	82	1.04	0.45 – 2.40	86	1.79	0.82 – 3.93	54	2.47	1.02 – 5.96
sCD30	82	0.93	0.51 – 1.68	86	2.00	1.02 – 3.91	54	4.85	1.92 – 12.28
sCD23	82	1.30	0.75 – 2.28	86	1.34	0.81 – 2.21	53	1.31	0.77 – 2.24
IgE	82	1.23	0.99 – 1.55	86	1.13	0.95 – 1.36	54	1.12	0.91 – 1.39
IL10	82	0.33	0.07 – 1.65	86	1.03	0.35 – 2.97	54	9.08	1.87 – 44.03

matched case-control sets

for all markers except IL10 ORs are in terms of one unit increase in natural log-transformed values; for IL10, ORs are in terms of detectable vs. undetectable. Statistically significant ORs are shown in bold.

sets matched on duration of HIV infection, analyses adjusted for age and CD4 T cell count

sets matched on time of initial AIDS diagnosis, analyses adjusted for age