Table 1. Tau expression is significantly increased in patients’ lymph node metastases.
Primary tumors and matched lymph node metastases from 102 patients were assessed for concordance and discordance of tau expression. The generalized McNemar’s test statistic is 10.2 with 3 degrees of freedom (P=0.0169), indicating a significant difference in tau score between the primary tumor and the metastases at significance level 0.05. Dark shaded region emphasizes the number of patients (n=27, 26%) that displayed increased tau expression in the lymph node metastases.
| 102 patients total | Met Score | |||
|---|---|---|---|---|
| 0 | 1 | 2–3 | ||
| Primary Score | 0 | 37 | 18 | 4 |
| 1 | 12 | 16 | 5 | |
| 2–3 | 0 | 0 | 10* | |
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*
indicates 10 patients with sustained strong tau staining in both primary and metastatic lesions.