Table 1.
Percentage growth inhibition by 50% (EC50: effective dose, causing 50% reduction of cell density during the 72 hrs incubation) by extracts from J. curcas roots. The following extracts were tested: hexane extract (JCRBH) and ethyl acetate extract (JCRBEA) as well as methanol extract (JCRBM). The three cells lines L5178y, PC12, and HeLa were used for the experiments.
| Extracts | Tumor cell lines, inhibitory concentration EC50 (μg/mL) | ||
|---|---|---|---|
| L5178y | PC12 | HeLa | |
| JCRBH | 0.82 ± 0.1 | 5.7 ± 0.6 | 1.7 ± 0.1 |
| JCRBEA | 2.2 ± 0.2 | >10.0 | 2.5 ± 0.3 |
| JCRBM | 3.7 ± 0.3 | >10.0 | 3.1 ± 0.3 |