Table 2.
Determination of alendronate sodium in the presence of possible excipients (5 μg mL−1 of alendronate sodium was taken for interferences studies).
| Excipient | Amount taken (g mL−1) |
% Recovery ± RSD (N = 5) method A |
% Recovery ± RSD (N = 5) method B |
|---|---|---|---|
| Microcrystalline cellulose | 300 | 99.6 + 0.25 | 99.6 + 0.25 |
| Anhydrous lactose | 300 | 99.5 + 0.25 | 99.5 + 0.25 |
| Magnesium stearate | 200 | 100.1 + 0.30 | 100.1 + 0.30 |
| Croscarmellose sodium | 100 | 99.8 + 0.40 | 99.8 + 0.40 |
| Calcium phosphate | 50 | 99.4 + 0.45 | 99.4 + 0.45 |