(c) Factors with additional roles in SG dynamics

Protein	Function	Cytoskeletal-association
eIF2B	Guanine nucleotide exchange factor for eIF2 [27]	Cytokeletal-associated [64]
eIF3	Recruited to SGs during disassembly [5, 27]	MT-associated [49]
eIF4E	mRNA 5′ cap binding protein [65]	Cytoskeletal-associated [66]
eIF4G	Early translation initiation factor [67]	Roles in F-actin localization/microtubule organization [68]
FXR1P	FRMP-associated protein [28]	MT-associated [50]
FXR2P	FMRP-associated protein [28]	MT-associated [50]
Hsp27	Granzyme-associated molecular chaperone [69]	Cytoskeletal-associated [70, 71]
HuD	ELAV/Hu family of RNA-binding proteins, mRNA localization [72]	MT-associated [73]
NAT1/p97	Related to eIF4G, translational repressor activated in apoptosis [74]	MT-associated [75]
PABP-1	Initiation factor binds poly(A) tail [38]	Binds mRNA to MT [76]
PMR1	mRNA decay endonuclease forms a complex with TIA-1 [77]	Cytoskeletal-associated through binding partners [78]
RACK1	Allows survival of stressed cells [1, 79]	Required for astral MT length [80]
Sam68	Nuclear RNA-binding protein [81]	Roles in cytoskeleton organization [82]
TRAF2	Allows survival of stressed cells [1, 83]	Regulates actin cytoskeleton [84]
Xrn1	5′-3′ exoribonuclease I [31, 85]	MT-associated [86]
YB1	SG stability [87, 88]	Binds mRNA to microtubules [76]
ZBP1	RNA-binding protein important for localized translation [89]	MT-associated [90]