Table 1.
| Pregnancy outcome variables | Prenatal Treatment Group | ||
|---|---|---|---|
| Control | Pair-Fed | PAE | |
| Number of pregnant dams | 15 | 8 | 9 |
| Maternal death | 0 | 0 | 1 |
| Perinatal death | 0 | 0 | 4 |
| Length of gestation (days) | 22.8±0.2 | 22.9±0.2 | 22.9±0.3 |
| Dam weight (grams) | |||
| Gestational Day 1 | 264.1±2.3 | 269.9±2.7 | 267.9±2.3 |
| Gestational Day 7 | 294.5±4.2 | 268.8±3.7 | 276.9±2.9 |
| Gestational Day 14 | 329.5±5.7 | 292.2±4.6 | 303.0±6.4 |
| Gestational Day 21 | 429.9±7.3 | 363.0±9.0* | 372.9±10.9* |
| Lactational Day 1 | 328.9±6.3 | 299.8±7.7 | 302.0±6.4 |
| Lactational Day 8 | 345.7±4.2 | 337.5±7.5 | 341.3±5.8 |
| Lactational Day 15 | 363.2±4.6 | 355.9±7.9 | 259.2±7.5 |
| Lactational Day 22 | 341.6±5.3 | 341.6±5.3 | 338.7±5.2 |
| Litter size | 15.8±0.3 | 16.1±0.5 | 15.3±0.7 |
| Offspring weight (grams) | |||
| Postnatal Day 1 | 6.4±0.1# | 5.69±0.1 | 5.6±0.2 |
| Postnatal Day 8 | 16.9±0.5 | 16.0±0.3 | 14.7±0.4 |
| Postnatal Day 15 | 32.8±0.7 | 31.2±0.8 | 29.9±0.6 |
| Postnatal Day 22 | 52.3±1.5 | 48.6±1.5* | 44.6±0.9* |
Developmental Data. Mean ± SEM. For dam weight data: *On Gestational Day 21: PAE=Pair-fed<Control (ps < 0.016). For offspring (females only) weight data: #Control > Pair-fed=PAE (ps < 0.01). *On Postnatal Day 22, PAE<Pair-fed<Control (ps < 0.01). PAE - animals prenatally exposed to alcohol.