Table 4.
Result of biomarkers in exhaled air, taking asthma severity into account
| GINA4 (n = 12) | GINA3 (n = 11) | Controls (n = 23) | Statistics1 | |
|---|---|---|---|---|
| FeNO50 a | 32.6 [16.8 - 70.9] | 27.6 [18.1 - 42.3] | 9.6 [8.4 - 14.2] | < 0.001 §,£ |
| CalvNO (ppb) a | 2.8 [2.0 - 2.8] | 4.4 [2.9 - 6.6] | 1.7 [1.1 - 2.8] | 0.003 § |
| J'awNO (nL/min) a | 79.0 [44.3 - 175.4] | 81.6 [58.5 - 114.4] | 30.9 [25.7 - 46.3] | 0.005 §,£ |
| NOx (μM) a | 12.5 [9.0 - 19.5] | 16.9 [14.0 - 19.7] | 9.9 [7.5 - 15.0] | 0.074 |
FeNO50: Fractional exhaled nitric oxide at 50mL/s, CalvNO: Alveolar NO concentration, J'awNO: Bronchial NO concentration, NOx: Oxides of nitrogen
a data expressed as geometric mean [IQR]
1 ANOVA
§ Significant increase GINA 3 vs controls
£ Significant increase GINA 4 vs controls