Table 1. Amino acid compositions of Sup35 and PrP fragments.
| Fragmenta | Ala | Arg | Asn | Asp | Cys | Gln | Glu | Gly | His | Ile | Leu | Lys | Met | Phe | Pro | Ser | Thr | Trp | Tyr | Val | Polarb |
| Sup35(1–114) | 4.4 | 1.8 | 17.5 | 1.8 | 0.0 | 28.1 | 0.0 | 16.7 | 0.0 | 0.0 | 0.9 | 0.9 | 0.9 | 1.8 | 4.4 | 3.5 | 0.0 | 0.0 | 17.5 | 0.0 | 49.1 |
| Sup35(1–39) | 7.5 | 2.5 | 22.5 | 2.5 | 0.0 | 32.5 | 0.0 | 10.0 | 0.0 | 0.0 | 0.0 | 0.0 | 2.5 | 0.0 | 0.0 | 7.5 | 0.0 | 0.0 | 12.5 | 0.0 | 62.5 |
| Sup35(40–114) | 2.7 | 1.3 | 14.7 | 1.3 | 0.0 | 26.7 | 0.0 | 20.0 | 0.0 | 0.0 | 1.3 | 1.3 | 0.0 | 2.7 | 6.7 | 1.3 | 0.0 | 0.0 | 20.0 | 0.0 | 42.7 |
| Sup35(65–104) | 2.5 | 2.5 | 12.5 | 2.5 | 0.0 | 27.5 | 0.0 | 20.0 | 0.0 | 0.0 | 0.0 | 2.5 | 0.0 | 5.0 | 10.0 | 0.0 | 0.0 | 0.0 | 15.0 | 0.0 | 40.0 |
| Human PrP ORD | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 14.6 | 0.0 | 51.2 | 9.8 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 12.2 | 0.0 | 0.0 | 12.2 | 0.0 | 0.0 | 24.4 |
a
Amino acids 1–114 of Sup35 encompass the entire PFD. Amino acids 1–39 are the nucleation domain, while amino acids 40–114 include the entire ORD. Amino acids 65–104 include the last 3½ repeats of the ORD.
b
Polar amino acids are Asn, Gln, His, Ser, and Thr.