Table 2.
Acute Toxicity (n=94)
| Toxicity | Grade |
||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| Auditory/hearing | 1 | 0 | 0 | 0 | 0 |
| Cardiovascular – (General) | |||||
| Edema NOS | 2 | 0 | 0 | 0 | 0 |
| Constitutional symptoms | 6 | 0 | 0 | 0 | 0 |
| Dermatology/skin | 4 | 0 | 0 | 0 | 0 |
| Endocrine | 1 | 0 | 0 | 0 | 0 |
| Gastrointestinal | 17 | 9 | 0 | 0 | 0 |
| Hemorrhage | 4 | 4 | 3 | 0 | 0 |
| Infection Febrile | 0 | 0 | 1 | 0 | 0 |
| Neutropenia | |||||
| Musculoskeletal | 0 | 1 | 0 | 0 | 0 |
| Neurology | 2 | 0 | 0 | 0 | 0 |
| Pain | 7 | 3 | 0 | 0 | 0 |
| Renal/Genitourinary | 35 | 42 | 4 | 0 | 0 |
| Sexual/Reproductive | 10 | 7 | 2 | 0 | 0 |
| Function | |||||
| Syndromes | 0 | 1 | 0 | 0 | 0 |
| Worst Overall | 28 | 48 | 8 | 0 | 0 |
Abbreviations: NOS=not otherwise specified