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. 2011 May 3;43(13):818–828. doi: 10.1152/physiolgenomics.00206.2010

Fig. 5.

Fig. 5.

RORαsg/sg(HFD) mice have increased energy expenditure. A–D: oxygen consumption (VO2) and carbon dioxide generation (VCO2) by WT(HFD) and RORαsg/sg(HFD) were analyzed by indirect calorimetry over a period of two 12 h light/12 h dark cycles. VO2, VCO2, VCO2/VO2, and heat generation were computed per kg free fat mass (WT, n = 5; RORαsg/sg, n = 6). E: comparison of the absolute values (per mouse) of VO2, VCO2, and heat generation between WT and RORαsg/sg mice. F: comparison of Ucp1 expression in BAT and muscle of WT and RORαsg/sg mice. Data present means ± SE. *P < 0.05, **P < 0.01, ***P < 0.001.