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. 2011 Jul;13(7):620–632. doi: 10.1593/neo.11134

Figure 1.

Figure 1

ACCA inhibits glucose mediated glioma invasiveness across Matrigel and organotypic brain slice cultures. Migration of EGFP-expressing glioma cells across Matrigel-coated transwell inserts or across 0.5-mm-thick coronal slices from the CPu region of immunodeficient rat brains were evaluated. Invasion across Matrigel of U87-MG (A) and U251-MG (C) (n = 4 per metabolite) or across coronal brain slices of U87-MG (B) and U251-MG (D) (n = 4 per metabolite) were plotted as fold invasion. Fold invasion = fluorescence of [(transwell bottom read)/(transwell top + bottom reads)]. Data shown as mean ± SEM. P values are indicated in comparison to glucose data. ***P < .01, **.01 < P < .05, *.05 < P < .1. Unmarked data sets had .1 < P < .5.