Table 3.

Postprandial output expressed as amount of the main pancreatic enzymes in the duodenal lumen in healthy adult humans^a

	Outputb	Collection condition	Method of measurement	Age, number, references
Lipase	54.9 ± 10.7c,d	Liquid test mealh	Tributyrin, pH 8.0, 37°C	22–42 yr, n = 15, Carrière34
	88.2 ± 25c,d	Liquid test mealh	Tributyrin, pH 8.0, 37°C	22–42 yr, n = 15, Carrière34
	245 ± 22c,e	Liquid test meali	Triolein emulsion, pH 8.0	23–30 yr, n = 6, Borovicka33
	442 ± 87d,f	Liquid test mealj	Enzyme immunoassay	22–40 yr, n = 6, Schwizer31
	253 ± 95g	Liquid test mealk	ELISA	20–50 yr, n = 3, Carrière38
	203 ± 96g	Liquid/solid test meall	ELISA	20–50 yr, n = 7, Carrière38
	416 ± 142c,e	Liquid/solid test mealm	Tributyrin, pH 8.0	21–25 yr, n = 6, Carrière35
Chymotrypsin	133 ± 50c,e	Liquid/solid test mealm	ATEE, pH 7.5, 37°C	21–25 yr, n = 6, Carrière35
Amylase	167 ± 133c,e	Liquid/solid test mealm	Starch, pH 6.9, 30°C	21–25 yr, n = 6, Carrière35

Notes:

^aSamples are duodenal aspirates;

^bOutput is expressed as total mg of proteins measured by immunoassay or specific ELISA test or

^cestimated using the known specific activity of enzymes (for pure human pancreatic lipase 8000 IU/mg on tributyrin or 1785 U/mg on triolein), and for

^d1-h period,

^e3-h period,

^f4-h period,

^g90-min period; For lipase activity measurement the authors also used a different concentration and type of bile salts that was not reported in the “Method of measurement.” Test meals:

^hFormula Shak Iso (500 mL, 14 g proteins [P], 12.5 g lipids [L], 52 g carbohydrates [C]);

ⁱFormula Ensure (500 mL, 16.8 g P, 13.4 g L, 53.4 g C);

^jFormula 10% Intralipid (500 mL, 550 kcal);

^kFormula Shak Iso (500 mL, 19 g P, 17 g L, 69 g G);

^lmixed solid/liquid meal (700 mL, 80 g string beans, 90 g beef meat, 70 g French fries, 10 g butter);

^mMixed solid/liquid meal (700 mL, 80 g string beans, 90 g beef meat, 70 g fried potatoes, 10 g butter, 15 mL olive oil).

Abbreviations: ATEE, N-acetyl-L-tyrosine ethyl ester; ELISA, enzyme-linked immunosorbent assay.