Table 3.
Fractions | Control | +TP2 |
LDL | 4 (0 - 6) | 0 (-5 - 1) |
HDL | 30a (26 - 38) | 18a,b (16 - 27) |
Percent transfer of 14C-PL from lipid emulsion to LDL and HDL obtained from fasting human plasma without (control) and with CETP monoclonal antibody, TP2, incubated for 30 minutes at zero (ice) and at 37°C. Plasma lipoproteins were fractionated by FPLC. Percent transfer was calculated as the difference between values obtained at 37°C and 0°C. Results are expressed as median (range), n=6. Mann-Whitney test: a: p<0.001 (HDL vs. LDL), b: p<0.05 (TP2 vs. control).