Table 2.
Quality control data for untreated control platelet concentrates (PCs) and UVC-treated PCs
| Parameter | Days after UVC irradiation |
|||||
|---|---|---|---|---|---|---|
| Day 1 |
Day 4 |
Day 6 |
||||
| control PC | PC-UVC | control PC | PC-UVC | control PC | PC-UVC | |
| PLT concentration × 109/ml | 1.19 ± 0.07 | 1.15 ± 0.04 | 1.15 ± 0.03 | 1.13 ± 0.04 | 1.13 ± 0.04 | 1.11 ± 0.05 |
| Swirling | OK | OK | OK | OK | OK | OK |
| pH | 7.17 ± 0.03 | 7.15 ± 0.05 | 7.34 ± 0.07 | 7.31 ± 0.08 | 7.34 ± 0.06 | 7.21 ± 0.04 |
| Glucose, mmol/l | 5.9 ± 0.5 | 5.9 ± 0.5 | 4.4 ± 0.4 | 4.1 ± 0.6 | 3.4 ± 0.6 | 2.6 ± 0.8† |
| Lactate, mmol/l | 8.5 ± 1.2 | 8.5 ± 1.0 | 10.8 ± 0.6 | 11.6 ± 1.1 | 12.6 ± 0.8 | 14.1 ± 1.3 |
| Hypotonic shock response, % | 79 ± 3 | 68 ± 8 | 62 ± 0 | 56 ± 7 | 57 ± 3 | 51 ± 1 |
| Collagen-induced aggregation, % 10 μg/ml collagen | 93 ± 4 | 93 ± 3 | 88 ± 4 | 89 ± 6 | 68 ± 12 | 77 ± 9 |
| Collagen-induced aggregation, % 2 μg/ml collagen | 33 ± 14 | 59 ± 7† | 23 ± 14 | 34 ± 12 | 7 ± 2 | 16 ± 7 |
| CD62, % | 44 ± 13 | 49 ± 3 | 38 ± 10 | 44 ± 2 | 47 ± 4 | 53 ± 4† |
| Annexin V, % | 4 ± 1 | 3 ± 1 | 6 ± 2 | 6 ± 2 | 7 ± 2 | 9 ± 2 |
| PAC-1 binding, Geo mean | 571 ± 127 | 727 ± 169† | 412 ± 115 | 488 ± 128† | 530 ± 193 | 610 ± 220 |
†
Significant at p < 0.05 (paired t-test).