(a) Superposition of IPCT (cartoon in blue) with several structures of RmlA: apo form (PDB code 1FZW; ribbon in dark green), and in complex with different ligands (PDB codes 1FXO, 1G0R, 1G2V, 1G1L, 1G23, and 1G3L; ribbons in different shades of green). dTDP-d-glucose (from 1G1L) is shown in sticks (C, yellow; O, red; N, blue; and P, orange). (b) IPCT active site pocket with fitted CDP-inositol; residues at the entrance are labeled.