Fig. 8.

NO· produced from nitrite by the AniA protein is bactericidal for an M. catarrhalis O35E norB mutant. Cells of the wild-type strain (wt), the norB mutant (norB), and the aniA norB mutant (aniA norB) were grown in BHI without or with the addition of 5 mM nitrite (+ nitrite). Aliquots from each culture were taken at the beginning (0 h) and end (6 h) of aerobic growth for the determination of viable cell counts (CFU/ml). The data shown are the means of results from three independent growth experiments.