Table 3.
Comparison of AtlA and AtlSa
| Parameter | Result for: |
|
|---|---|---|
| AtlA | AtlS | |
| Origins | S. mutans | S. gordonii |
| Encoding genes | SMu0630 | SGO2013 |
| Gene locus | Multigene operon | Single-gene operon |
| Protein characteristics | 977 amino acids, 107 kDa, and has a conserved β1,4-N-acetylmuramidase domain located at C-terminal (3) | 1,160 amino acids, 127 kDa, and has a conserved β1,4-N-acetylmuramidase domain located at N-terminal |
| Involvement in the cell physiology | Normal cell wall biosynthesis, stress tolerance, autolysis, competence, and biofilm formation (3, 4) | Normal cell wall biosynthesis, stress tolerance, autolysis, and biofilm formation |
| Contribution to eDNA release | NR | Major |
| Processing for protein maturation | Cleavage (3) | Cleavage |
| Inducible conditions | Oxidative stress (4) | Oxidative stress and CSP |
| Transcriptional regulation | ||
| Promoter | At least three promoters (3) | One proximal promoter |
| Regulator | NR | VicRK and LytST |
| Direct regulator | NR | LytT |
| Posttranscription regulation | ThmA, Smu0629, and VicRK (4) | ND |
a
NR, not reported; ND, not determined.