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. 2011 May;31(9):1870–1884. doi: 10.1128/MCB.01393-10

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Fig. 4. — Arnt-independent regulation of mTORC1 by hypoxia in hepatocytes. (A) Western blot analysis of wild-type hepatocytes exposed to hypoxia for the indicated number of hours. Ppib, cyclophilin B. (B and C) X-Gal staining (B) and Western blot (C) of hepatocytes of the three different genotypes exposed to hypoxia for the indicated number of hours. (D) Wester blot of Ad-Cre-transduced Arnt^F/F and Arnt^+/+ hepatocytes exposed to hypoxia for the indicated number of hours. (E) Western blots of wild-type hepatocytes, treated with Ad-Cre or not treated with Ad-Cre (−), and exposed to hypoxia for the indicated number of hours.