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Depletion of CELF2 to reduce LEF1 exon 6 inclusion inhibits signal-induced TCR-alpha expression. (A) Graph of LEF1 exon 6 inclusion (top) and TCR-alpha mRNA (bottom) in cells depleted of CELF2 using the shRNA as described in the legend to Fig. 6. Error bars indicate standard deviations from 2 or 3 independent experiments in cells grown for 48 h in the absence (−) or presence (+) of PMA. Values are shown relative to the JSL1 control. (B) Same as panel A for cells expressing miR-23b.
