Fig. 5.

Alignment of RafK and MalK protein sequences showing homology. Annotated are typical ABC transporter motifs (Walker A, Lid, Signature, Walker B, D-loop, Switch), the start of the regulatory domain (RD Start), regulatory domain motif 1 (RDM1), and regulatory domain motif 2 (RDM2). Residues in bold are considered important conserved residues in the regulatory domain. Secondary structures of the regulatory domain of E. coli MalK are given under the sequences, with α representing α-helices with corresponding numbers and β representing β sheets with corresponding numbers.