Fig. 4.
Hepatocyte-specific Snai1 deletion verified by the R26R reporter strain. (A) CKO mice were bred to the R26R reporter strain so that albumin-Cre transgene activity would result in recombination of the loxp-flanked STOP cassette in the R26R allele, allowing lacZ gene expression and β-galactosidase activity in hepatocytes. (B) Liver tissue was isolated from R26R+/− Snai1loxp/loxp mice with or without the albumin-Cre transgene. Whole tissue was stained for β-galactosidase activity (blue), sectioned, and counterstained with eosin, followed by examination by light microscopy. Scale bar = 50 μm.