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. Author manuscript; available in PMC: 2012 Jun 15.
Published in final edited form as: J Immunol. 2011 May 4;186(12):7187–7194. doi: 10.4049/jimmunol.1100412

Figure 7. Decreased Il-18 production in Nlrp6-deficient mice during inflammation-induced tumorigenesis.

Figure 7

Serum was collected from age- and sex-matched untreated (N=3 mice/group) and AOM/DSS-treated Nlrp6−/− and wildtype mice on days 7 to 13 (N=5 to 9 mice/group/timepoint). IL-18 was measured by ELISA. B, Colon tissue protein extracts were made from untreated (N=4 mice/group) and AOM/DSS-treated mice (N=5 mice/group) sacrificed on day 11. IL-18 was measured by ELISA and normalized by colon weight. Data expressed as means +/− S.E.M., *, p<0.05 by Student’s t-test.