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. 2010 Feb 4;2(2):547–565. doi: 10.3390/v2020547

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© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 2. — The in vitro activities of the selected mAbs against HIV-1 infection in a pseudovirus/cell line neutralization assay. The antibodies in Fab format were tested against two clade B primary R5 isolates, Bal (a) and JRFL (b), and a clade B lab-adapted X4 isolate, IIIB (c). A CD4i human antibody domain (domain antibody, dAb), m36, was used as a positive control and an irrelevant human dAb targeting the human insulin-like growth factor 2 (IGF-2), 1A1, was used as a negative control.