. Author manuscript; available in PMC: 2012 Aug 1.

Published in final edited form as: Arch Biochem Biophys. 2011 May 27;512(1):1–23. doi: 10.1016/j.abb.2011.05.010

Table 1.

Mg²⁺ Transporters in Mammalian Cells

	Family	Members	Apparent Km	Type of Transporter	Ref.
Entry Mechanisms
Cell Membrane	TRPM	TRPM6	~0.7 Mm	Channel	43
		TRPM7	~0.7 mM	Channel	42
	Claudins	claudin 16 (PCLN-1)	~0.7mM	Channel	92
		claudin-19	~0.7mM	Channel	100
	MagT1	MagT1	0.2 mM	Channel	101,103
	SLC41	SLC41A1	0.7 – 3 mM	Carrier(?)*	147
		SLC41A2	0.7 – 3 mM	Carrier(?)	150,151
	ACDP	ACDP1	~0.7 mM	Carrier	152
		ACDP2	~0.5 mM	Carrier	153
	NIPA	NIPA1 (SPG6)	0.7 mM	Carrier	157
		NIPA2	0.7 mM	Carrier	158
	Huntingtin	Huntingtin1 (HIP14)	0.87 mM	Carrier	160
		HIP14L	0.74 mM	Carrier	160
Mitochondria	Mrs2	Mrs2/AtMrs2, Lpe10	~1.5 mM	Channel	106
Golgi	MMgt	MMgT1	1.5 mM	Channel	112
		MMgT2	0.6 mM	Channel	112
Exit Mechanisms
Cell Membrane	Na⁺/Mg²⁺ exchanger	ND	15–20 mM	antiport	131,133
	Na⁺-Independent	ND (choline?)	~20mM	exchanger(?)	137
	SLC41	SLC41A1	~0.7 mM	Carrier(?)*	149
	H⁺/Mg²⁺ exchanger	AtMHX^#	~15mM	exchanger	141

Identified only in plants and yeast and not in mammalian/human cells.