Table 1.
Characteristics of RA subjects who remained erosion free over 2 years compared with subjects with erosions (n = 271)
| Characteristic | Erosion free, n (%) = 56 (20.7) | Erosions present, n (%) = 215 (79.3) | P-value |
|---|---|---|---|
| Age at onset, mean (s.d.), years | 45.0 (14.6) | 51.3 (13.2) | 0.0026 |
| Gender: female, n (%) | 44 (78.6) | 175 (81.4) | 0.63 |
| Disease duration, mean (s.d.), years, | 3.4 (3.0) | 4.5 (3.1) | 0.03 |
| Tobacco use (ever/never), n (%) | 25 (44.6) | 103 (47.9) | 0.46 |
| BMI, mean (s.d.) | 27.4 (5.9) | 26.5 (5.3) | 0.34 |
| Fulfils 1987 ACR criteria, n (%) | 55 (98.2) | 209 (97.2) | 0.68 |
| Functional assessment | |||
| MDHAQ, mean (s.d.) | 1.4 (1.5) | 1.9 (1.4) | 0.018 |
| DAS | |||
| DAS, mean (s.d.) | 3.7 (1.7) | 3.8 (1.5) | 0.65 |
| Swollen joint count, mean (s.d.) | 6.1 (7.2) | 6.4 (6.8) | 0.72 |
| Tender joint count, mean (s.d.) | 7.8 (8.5) | 7.0 (7.2) | 0.49 |
| Baseline JSN score, median (IQR) | 0 (0) | 2 (0,10) | <0.0001 |
| Serological studies | |||
| RF positive, n (%) | 24 (42.9) | 112 (52.1) | 0.22 |
| Anti-CCP positive, n (%) | 26 (46.4) | 121 (56.3) | 0.19 |
| CRP titre, median (IQR), mg/dl | 3.6 (1.3, 8.7) | 2.8 (0.95, 6.3) | 0.53 |
| Medications at baseline, n (%) | |||
| MTX | 24 (42.9) | 97 (45.1) | 0.76 |
| TNFi | 15 (26.8) | 61 (28.4) | 0.81 |
| HCQ | 10 (17.9) | 54 (25.1) | 0.26 |