Table 4.
Hemorheological indices
| Item | Blank control group | Ischemic control group | Ethosome patch group | Introderm TTS group |
|---|---|---|---|---|
| Whole blood viscosity (high shear) | 4.56 ± 0.96 | 5.94 ± 0.94a | 5.19 ± 0.78c | 5.58 ± 0.74b |
| Whole blood viscosity (middle shear) | 5.80 ± 1.14 | 7.30 ± 1.21a | 6.45 ± 0.95c | 6.84 ± 1.00c |
| Whole blood viscosity (low shear) | 9.13 ± 2.08 | 13.83 ± 2.73a | 11.43 ± 1.90c | 12.68 ± 2.44c |
| Plasma viscosity | 0.97 ± 0.07 | 1.40 ± 0.10a | 1.08 ± 0.05c | 1.21 ± 0.08c |
| hematocrit | 5.64 ± 1.24 | 8.32 ± 1.90a | 7.00 ± 0.92c | 7.65 ± 1.35b |
| RBC aggregation index | 8.19 ± 1.71 | 12.17 ± 2.43a | 9.89 ± 1.80c | 11.37 ± 2.18c |
| RBC deformation index | 0.49 ± 0.19 | 0.80 ± 0.12a | 0.60 ± 0.14c | 0.72 ± 0.16c |
Notes: Compared with blank control group:
a
P < 0.01; compared with ischemic control group:
b
P < 0.05;
c
P < 0.01.
Abbreviations: RBC, red blood cells; TTS, transdermal therapeutic system.