Table 1.

Effects of E162-Water on NMBA-Induced Precancerous Lesion Formation in the Esophagi of F344 Rats

Group	Normal	Epithelial hyperplasia	Dysplasia	Papillomas
1 (DMSO)	97.6 ± 4.6	2.4 ± 4.6	None	None
2 (E162-water)	92.9 ± 16.0	7.1 ± 16.0	None	None
3 (NMBA)	22.8 ± 9.6	48.1 ± 12.5	29.1 ± 13.9	11.39 ± 0.97
4 (NMBA + E162-water)	25.2 ± 11.4	52.7 ± 13.1	22.1 ± 15.4a	6.21 ± 0.58b

Data are mean ± SD values.

Statistically significant relative to the NMBA group as determined by analysis of variance: ^aP < .01, ^bP < .001.