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. 2011 Jul 11;6(7):e21478. doi: 10.1371/journal.pone.0021478

Figure 1. A bi-transgenic system for conditional and reversible suppression of VEGF signaling in the liver.

Figure 1

(a) A schematic representation of the driver and responder transgenes used in the bi-transgenic system (b) Northern blot analysis of hepatic and renal RNA with a probe specific for transgenic (human) VEGF-R1. The term “off” indicates control littermates; “on” indicates that sVEGF-R1 expression was induced for 1 month in two transgenic animals. Note the tissue specific expression of the transgene.