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Water Pockets in Ubiquitin: on the left is water pocket-U, which is located at the loop region of residues 18 to 22. Water molecules in this pocket form hydrogen bonds with the Glu 18 and Asp 21 carbonyl oxygens. On the right is water pocket V, which is located between beta-sheet III and beta-sheet IV. Water molecules in this pocket form hydrogen bonds with the Leu 43 nitrogen and the Leu 50 carbonyl oxygen.
