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Diagnostic criteria for Waldenström macroglobulinemia (1)
| IgM monoclonal gammopathy of any concentration |
| Bone marrow infiltration by small lymphocytes showing plasmacytoid or plasma cell differentiation |
| Intertrabecular pattern of bone marrow infiltration |
| Cell Surface Markers |
| IgM+CD5±CD10−CD19+CD20+CD22+CD23−CD25+CD27+FMC7+ |
| CD103−CD138−. Variations from this phenotypic profile can occur. |
