Table 1.
Micro-CT results of control vs. regenerated bone (mean ± SD)
| Bone index | Week 12
|
Week 18
|
Weeka | Tissue typeb | Tissue type*weekc | ||
|---|---|---|---|---|---|---|---|
| Control | Regenerate | Control | Regenerate | P≤ | P≤ | P≤ | |
| Apparent density (mgHA/cm3) | 506.03 ± 60.71 | 333.71 ± 98.88 | 602.96 ± 77.76 | 476.36 ± 71.00 | 0.036 | 0.000 | 0.127 |
| Material density (mgHA/cm3) | 853.31 ± 14.62 | 689.89 ± 18.53 | 852.99 ± 19.07 | 735.19 ± 31.28 | 0.051 | 0.000 | 0.047 |
| Bone volume (mm3) | 366.54 ± 49.51 | 139.74 ± 54.73 | 306.03 ± 47.72 | 323.24 ± 180.51 | 0.260 | 0.025 | 0.013 |
| Total volume (mm3) | 585.02 ± 54.35 | 296.23 ± 151.42 | 425.52 ± 42.87 | 475.91 ± 231.90 | 0.888 | 0.072 | 0.018 |
| BV/TV (%) | 63 ± 5 | 52 ± 12 | 72 ± 8 | 66 ± 7 | 0.051 | 0.002 | 0.211 |
| Tb.BV/TV (%) | 25 ± 7 | 52 ± 12 | 25 ± 9 | 66 ± 7 | 0.253 | 0.000 | 0.004 |
| Tb.BS/BV (1/mm) | 11.66 ± 2.18 | 7.06 ± 2.00 | 11.87 ± 1.54 | 4.9 ± 1.30 | 0.404 | 0.000 | 0.001 |
| Trabecular thickness (mm) | 0.18 ± 0.04 | 0.30 ± 0.09 | 0.17 ± 0.02 | 0.43 ± 0.11 | 0.162 | 0.000 | 0.022 |
| Trabecular separation (mm) | 0.53 ± 0.08 | 0.28 ± 0.07 | 0.57 ± 0.20 | 0.22 ± 0.04 | 0.888 | 0.000 | 0.273 |
| Trabecular number (1/mm) | 1.43 ± 0.12 | 1.74 ± 0.19 | 1.42 ± 0.39 | 1.59 ± 0.29 | 0.409 | 0.137 | 0.626 |
| Connectivity density (1/mm3) | 7.48 ± 1.39 | 11.37 ± 2.37 | 7.52 ± 3.00 | 10.85 ± 6.38 | 0.900 | 0.049 | 0.863 |
a
Week is the test of between-subjects effect of consolidation time (Week 12 vs. Week 18)
b
Tissue type is the test of within-subjects effect of distraction osteogenesis (Control vs. Regenerate)
c
Tissue type*week is the test of the Interactive effect of distraction osteogenesis and consolidation time
BV/TV total bone volume fraction, Tb. BV/TV trabecular bone volume fraction, Tb. BS/BV trabecular bone surface ratio